A Developer Brain is not like an ordinary person brain, he has experienced things ordinary people never had, that led that organ to grow in a complex way, the below diagram i found is the best to describe it.

Web Developer Brain

This is a known issue in Leopard, basically the system is looking for the mysql.sock file in the wrong place. Just need to create a symlink and you should be in business:

sudo mkdir /var/mysql/
sudo ln -s /tmp/mysql.sock /var/mysql/mysql.sock